ELISA (Enzyme-Linked Immunosorbent Assay) is the primary “workhorse” of HIV screening. Modern 4th-generation ELISA tests are “combo” assays; they look for both HIV-1/2 antibodies and the p24 antigen. Because the p24 antigen appears before antibodies develop, this test can detect an infection as early as 2–3 weeks after exposure
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