The “C” stands for Cytoplasmic: When the antibodies in your blood are applied to healthy white blood cells in the lab, they attach to the cytoplasm (the jelly-like fluid inside the cell).
The Visual Result: Under a fluorescent light, the entire body of the cell glows with a “granular” or “speckled” appearance, while the center (the nucleus) remains dark.
The Target: This pattern almost always indicates that the body is attacking an enzyme called Proteinase 3 (PR3).
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