CD4 is a glycoprotein found on the surface of “Helper” T-cells. These cells are the “generals” of the immune system; they don’t kill pathogens directly but instead coordinate the response of other immune cells.
- The Diagnostic Role: In pathology, CD4 helps determine the specific subtype of a T-cell population.
- The IHC Advantage: Unlike a blood test, IHC shows exactly where the CD4 cells are situated—for example, are they surrounding a tumor, or are they the ones forming the tumor itself?
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