The “P” stands for Perinuclear: When your antibodies are added to test cells in the lab, they cluster specifically around the nucleus (the command center of the cell).
The Visual Result: Under a fluorescent microscope, you see a bright ring of light hugging the nucleus, while the outer cytoplasm of the cell remains dark.
The Target: This pattern usually indicates that the immune system is attacking an enzyme called Myeloperoxidase (MPO).
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